Investors often assume the biggest returns come from bold calls or perfectly timed trades.
In reality, some of the strongest outcomes on the ASX have come from simply owning high-quality businesses and giving them time to do their thing.
With that in mind, here are five ASX shares that have the kind of foundations that can quietly compound wealth over long periods.
CSL Ltd (ASX: CSL)
The first ASX share to consider is CSL. It operates in markets driven by long-term healthcare demand rather than short-term economic cycles. Its therapies treat chronic and life-threatening conditions, which creates resilient demand and pricing power over time.
Heavy reinvestment in R&D and plasma collection has weighed on margins at times, but that investment mindset is also what has allowed CSL to grow into a global leader. And with its shares down heavily from their highs due to short-term headwinds, now could be an opportune time to invest.
Goodman Group (ASX: GMG)
Another ASX share worth highlighting is Goodman Group. It has evolved well beyond a traditional property trust. Goodman develops and owns high-quality logistics facilities and data centres in global cities, often in partnership with long-term capital providers.
As ecommerce, supply chain optimisation, and data infrastructure demand continue to rise, Goodman’s development pipeline and capital recycling model provide a pathway for ongoing growth rather than static rental income.
Pro Medicus Ltd (ASX: PME)
A third ASX share that fits the long-term compounding theme is Pro Medicus. It provides mission-critical imaging software to hospitals and health systems. Once embedded, its platform becomes deeply integrated into clinical workflows, making customer churn extremely low.
As healthcare systems modernise and imaging volumes grow, Pro Medicus benefits from both new contract wins and expanding usage within existing customers, a powerful combination for sustained earnings growth. Morgans just upgraded its shares today on the belief that AI disruption concerns are unwarranted.
REA Group Ltd (ASX: REA)
Another ASX share that has quietly built enormous value is REA Group. It owns Australia’s dominant online property platform, giving it exposure to property transactions without the balance sheet risk of owning property itself. Its scale advantage allows it to monetise listings, data, and advertising more effectively than any competitor.
While property markets move in cycles, REA’s position at the centre of buyer and seller activity has allowed it to grow earnings through multiple housing booms and slowdowns.
ResMed Inc. (ASX: RMD)
A final ASX share with long-term compounding potential is ResMed. It is the leading player in sleep disorder treatment solutions. Rising awareness of sleep apnoea and chronic respiratory conditions continues to expand its addressable market.
Beyond devices, ResMed’s growing software and data platforms are strengthening customer relationships and recurring revenue. That combination gives the business multiple levers for growth over time.
The post 5 amazing ASX shares that could build serious wealth for investors appeared first on The Motley Fool Australia.
Should you invest $1,000 in CSL right now?
Before you buy CSL shares, consider this:
Motley Fool investing expert Scott Phillips just revealed what he believes are the 5 best stocks for investors to buy right now… and CSL wasn’t one of them.
The online investing service he’s run for over a decade, Motley Fool Share Advisor, has provided thousands of paying members with stock picks that have doubled, tripled or even more.*
And right now, Scott thinks there are 5 stocks that may be better buys…
* Returns as of 1 Jan 2026
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More reading
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- Morgans upgrades 3 ASX shares to buy ratings
- Why Elevra Lithium, Pro Medicus, Sims, and Treasury Wine shares are roaring higher
Motley Fool contributor James Mickleboro has positions in CSL, Goodman Group, Pro Medicus, REA Group, and ResMed. The Motley Fool Australia’s parent company Motley Fool Holdings Inc. has positions in and has recommended CSL, Goodman Group, and ResMed. The Motley Fool Australia’s parent company Motley Fool Holdings Inc. has recommended Pro Medicus. The Motley Fool Australia has positions in and has recommended ResMed. The Motley Fool Australia has recommended CSL, Goodman Group, and Pro Medicus. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.