
If you’re building a $250,000 ASX share portfolio, you might want to focus on quality, diversification, and businesses with positive long-term growth outlook.
Here is how you could structure it if you were doing it today:
ResMed Inc. (ASX: RMD)
The first building block could be ResMed. Sleep apnoea and respiratory disorders are long-term health issues that are not going away. As populations age and obesity rates rise, demand for sleep therapy devices continues to grow.
ResMed also has a fast-growing software-as-a-service platform that supports healthcare providers. That recurring revenue stream adds resilience and higher-margin earnings to the core device business.
For a portfolio foundation, you might want exposure to a company that can grow steadily regardless of the economic cycle. ResMed arguably ticks that box.
Goodman Group (ASX: GMG)
Goodman is not a traditional property landlord. It specialises in logistics facilities and data centres in prime global locations. As ecommerce expands and cloud computing demand rises, these assets become increasingly valuable.
The company’s development pipeline and partnerships give it flexibility to scale with customer demand. It is exposed to structural shifts in supply chains and digital infrastructure, not just local property cycles.
This combination of real assets and growth exposure could make it a compelling long-term holding for a portfolio.
Macquarie Group Ltd (ASX: MQG)
To round out Australian blue-chip exposure, you might want to include an ASX share like Macquarie.
Macquarie has built a global asset management and infrastructure franchise. Its earnings are diversified across asset management, commodities, investment banking, and infrastructure operations.
Over decades, it has shown an ability to adapt and find new profit pools. For a long-term portfolio, you might want at least one company with proven capital allocation skills and international reach. Macquarie provides both.
Betashares Nasdaq 100 ETF (ASX: NDQ)
For global growth exposure, you could allocate a meaningful portion to the Betashares Nasdaq 100 ETF.
This ASX exchange trade fund (ETF) gives access to many of the world’s best companies, including major players in technology, consumer platforms, and artificial intelligence.
Rather than trying to pick the single best US tech stock, this fund provides broad exposure to the leaders driving global digital transformation.
VanEck Morningstar Wide Moat ETF (ASX: MOAT)
Finally, you could add the VanEck Morningstar Wide Moat ETF.
This ASX ETF focuses on US-based stocks with sustainable competitive advantages with fair valuations. It is designed around the idea of owning businesses with economic moats that protect profits over time.
The VanEck Morningstar Wide Moat ETF adds a disciplined quality overlay to the portfolio and complements the more growth-oriented the Betashares Nasdaq 100 ETF allocation.
The post How to build a $250,000 ASX share portfolio from scratch today appeared first on The Motley Fool Australia.
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* Returns as of 20 Feb 2026
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- New to the share market? Here are 3 ASX ETFs to buy for easy investing
Motley Fool contributor James Mickleboro has positions in BetaShares Nasdaq 100 ETF, Goodman Group, ResMed, and VanEck Morningstar Wide Moat ETF. The Motley Fool Australia’s parent company Motley Fool Holdings Inc. has positions in and has recommended BetaShares Nasdaq 100 ETF, Goodman Group, Macquarie Group, and ResMed and is short shares of BetaShares Nasdaq 100 ETF. The Motley Fool Australia has positions in and has recommended BetaShares Nasdaq 100 ETF, Macquarie Group, and ResMed. The Motley Fool Australia has recommended Goodman Group and VanEck Morningstar Wide Moat ETF. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.