Insider Monkey has processed numerous 13F filings of hedge funds and successful value investors to create an extensive database of hedge fund holdings. The 13F filings show the hedge funds' and successful investors' positions as of the end of the first quarter. You can find articles about an individual hedge fund's trades on numerous financial […]

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Shares in IMV Inc. (IMV) are spiking 134% in Tuesday’s pre-market trading after the clinical-stage biopharma company said it made “rapid progress” in developing its candidate vaccine to prevent COVID-19 infection.The stock surged to $4 in pre-market trading as IMV said that it was working closely with regulatory agencies and its partners to initiate clinical studies as quickly as possible. The plan for the Phase 1 clinical study, agreed with Health Canada, is a randomized controlled study, assessing the safety and immunogenicity of its vaccine candidate DPX-COVID-19, to be conducted in 84 healthy adults across two age cohorts.DPX-COVID-19, is based on the Canadian biotech’s first-in-class lipid-based vaccine delivery platform that generates targeted and sustained immune response in vivo. Fully synthetic, the vaccine candidate is designed to focus the immune response on the weaknesses of the virus with the goal to optimize safety and efficacy.“The rapid progress in target selection, the vaccine formulation, manufacturing and preclinical results so far not only demonstrate the potential of our delivery platform, but also build on our previously reported clinical data from a similarly designed vaccine against RSV, the respiratory syncytial virus,” says IMV CEO Frederic Ors. “Clinical results have shown our DPX-based vaccine against RSV demonstrated a unique ability to generate safe and long-lasting immune responses in older adults.”IMV, a pioneer in a novel class of cancer immunotherapies and vaccines against infectious diseases, said it expects to start first in-human Phase 1 clinical trials this summer with results due in the fall of this year. Once results are published, the biotech company plans to initiate Phase 2 clinical trials in the second half of the year.Shares in IMV have more than doubled since hitting a low in March and are now trading 2.8% higher than at the beginning of the year. Overall, Wall Street analysts have a cautiously optimistic outlook on the stock with a Moderate Buy consensus. Despite the recent rally, the $6.21 average analyst price target implies a whopping 107% upside potential to current levels. (See IMV stock analysis on TipRanks)Related News: Abbott Labs, Edwards Lifesciences Settle Heart Device Patent Disputes Aldeyra Spikes 10% In Pre-Market On New Perceptive Stake Equillium Explodes 260% On Positive Covid-19 Results; India Approval More recent articles from Smarter Analyst: * Google In Talks To Buy $4B Stake In India’s Jio Platform – Report * Tesla Climbs 6% In Pre-Market, Boosted By ‘Accelerating’ China Projects * Biogen, Eisai Start New Phase 3 Trial For Pre-clinical Alzheimer’s Disease * AMC To Cut Debt By Up To $630M Lifting Shares By 7% In Pre-Market

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While not a mind-blowing move, it is good to see that the Cara Therapeutics, Inc. (NASDAQ:CARA) share price has gained…

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The San Francisco-based bank also cut its dividend for the third quarter to 10 cents per share from 51 cents previously to reflect the U.S. Federal Reserve’s recent curbs on bank dividends. Net interest income fell 18% from the prior period, as interest rates have fallen to near zero.

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The San Francisco-based bank also cut its dividend for the third quarter to 10 cents per share from 51 cents previously to reflect the U.S. Federal Reserve’s recent curbs on bank dividends. Net interest income fell 18% from the prior period, as interest rates have fallen to near zero.

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Tesla Inc (TSLA) has met with officials from a district in the city of Chongqing in southwestern China to discuss “accelerating projects”, the Liangjiang New Area said on Tuesday, as reported by Reuters.According to the report, officials held meetings with Tesla Vice-president Tao Lin, whose visit was reportedly welcomed by government official Duan Chenggang to “promote cooperation.”Reuters also reports unidentified sources cited by the China Securities Journal stating that cooperation could refer to sales and maintenance centers rather than factories. Last year Tesla opened its first plant outside the US in Shanghai.Shares in Tesla are climbing 6% in Tuesday’s pre-market trading, with the electric vehicle maker now up a whopping 265% year-to-date. The rally has continued unabated following strong second-quarter car deliveries, which exceeded analysts’ expectations. It delivered about 90,650 vehicles during the quarter, easily beating the estimated 74,130 figure.Piper Sandler analyst Alexander Potter has just boosted his price target on Tesla to $2,322 from $939 while reiterating his buy rating. According to Potter, Tesla is the “most consequential company in the mobility ecosystem, and this is unlikely to change in the next decade.” He recommends investors hold on to shares, noting the company’s significant software opportunity and faster-than-expected share gains.Looking ahead, five-star analyst Daniel Ives at Wedbush says that although investors will be focusing next on 2Q earnings on July 22, he continues to believe that Battery Day now to be held on Sept. 22 will be a major positive catalyst for the stock.“First on earnings around the corner, based on the 90k delivery number that Musk & Co. announced a few weeks ago it appears profitability is likely on the horizon and will be another major feat for Tesla in this very arduous COVID-19 backdrop,” Ives told investors.However, the analyst maintained a Hold rating on the stock with a $1,250 price target. Like Ives the majority of Wall Street analysts are sidelined on the stock with a Hold analyst consensus. In light of the share’s rally this year, the $905 average analyst price target now implies 39% downside potential to current levels. (See Tesla’s stock analysis on TipRanks).Related News: Google Faces Antitrust Investigation From Its Home State, California Apple Pledges $400M To Address California’s Housing Crisis Microsoft To Spin-Off Xiaoice, China’s Teenage Chatbot More recent articles from Smarter Analyst: * Biogen, Eisai Start New Phase 3 Trial For Pre-clinical Alzheimer’s Disease * AMC To Cut Debt By Up To $630M Lifting Shares By 7% In Pre-Market * Microsoft, Samsung To Develop Online Portal For Smart Building Management * Amazon’s Smart Cart Allows You To Skip The Line, And Will Launch This Year

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Biogen (BIIB), in collaboration with Eisai, and the Alzheimer’s Clinical Trials Consortium, has initiated a new global Phase 3 clinical study (AHEAD 3-45) with BAN2401, an anti-amyloid beta (Aβ) protofibril antibody.The study will evaluate the therapeutic effect of BAN2401 on the progression of Alzheimer’s disease in individuals in preclinical (asymptomatic) stages of the disease. These patients are clinically normal and have intermediate or elevated levels of amyloid in their brains.The AHEAD 3-45 program consists of two trials, A3 and A45, which aim to evaluate the potential of BAN2401 to reduce accumulation of harmful amyloid beta aggregates in the brain and prevent cognitive decline due to Alzheimer’s disease.A total of 1400 participants will be enrolled in the study, and will be conducted in the US, Canada, Japan, Australia, Singapore and Europe.The A3 trial will enroll participants with an intermediate amount of amyloid in the brain and high risk for further amyloid beta accumulation, and thus at risk for developing clinical symptoms of Alzheimer’s disease. The aim is to evaluate the potential of BAN2401 to stop or reduce aggregation of harmful amyloid beta in the brain before any clinical symptoms develop.The A45 trial will enroll participants with elevated levels of amyloid beta in the brain. The trial will measure the effect of BAN2401 in preventing cognitive decline and suppressing progression of Alzheimer’s disease pathology in the brain.“A successful outcome would provide opportunities to treat patients at a very early stage, or even preventing the disease, thereby substantially reducing patients’ suffering and providing substantial cost savings for society at large,” commented Gunilla Osswald, CEO, of Eisai’s business partner, BioArctic AB.Shares in Biogen are down 6% year-to-date, and analysts have a cautious Hold consensus on the stock. That’s with 8 recent buy ratings, vs 13 holds and 4 sells. Meanwhile the average analyst price target stands at $309 (12% upside potential). (See BIIB stock analysis on TipRanks)On July 8 Biogen announced that it had completed its biologics license application (BLA) regulatory submission for aducanumab, an investigational human monoclonal antibody for Alzheimer’s disease- and requested priority review. The US regulatory body, the FDA, now has 60 days to accept the filing, which will kick off a review of the application.JP Morgan’s Cory Kasimov anticipates that BIIB will receive Priority Review given the unmet medical need and expects the FDA to hold an Advisory Committee to get experts to weigh in on the package; this would likely occur in 2H20 under a priority review.“That said, this does not change our view on the candidate’s approval prospects, which we currently see as little better than a coin flip” the analyst wrote, adding that “with mounting pressures to the core franchises lowering BIIB’s perceived floor valuation, everything appears to be riding on this single, controversial asset.” As a result he reiterated a Hold rating on Biogen.Related News: Aldeyra Spikes 10% In Pre-Market On New Perceptive Stake Equillium Explodes 260% On Positive Covid-19 Results; India Approval Abbott Labs, Edwards Lifesciences Settle Heart Device Patent Disputes More recent articles from Smarter Analyst: * AMC To Cut Debt By Up To $630M Lifting Shares By 7% In Pre-Market * Microsoft, Samsung To Develop Online Portal For Smart Building Management * Amazon’s Smart Cart Allows You To Skip The Line, And Will Launch This Year * Google Seeks To Reassure EU For Fitbit Merger Approval- Report

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(Bloomberg) — China will impose unspecified sanctions on defense contractor Lockheed Martin Corp. after the U.S. approved a possible $620 million deal to supply missile parts to Taiwan, marking the latest in a volley of punitive actions by the superpowers as relations grow colder.“China firmly opposes U.S. arms sales to Taiwan,” Chinese Foreign Ministry spokesman Zhao Lijian said at a briefing in Beijing on Tuesday. “We will impose sanctions on the main contractor of this arms sale, Lockheed Martin,” he said, without elaborating on what form the sanctions may take.The move comes as tensions grow between the U.S. and China on a number of fronts, from the trade war and territorial claims in the South China Sea to the coronavirus pandemic and new security law Beijing imposed on Hong Kong. Zhao, the Foreign Ministry spokesman, called on the U.S. to cut military ties with Taiwan — which China considers part of its territory — to avoid “further harm to bilateral relations.”“It’s tit-for-tat between the two countries,” said Shukor Yusok, founder of aviation consultancy Endau Analytics in Malaysia. “The impact this time is going to be small, but it could be the start of more to come.”U.S. arms manufacturers face strict limitations on what kind of business they can do with countries deemed by Washington to be strategic rivals, such as China. Lockheed generated 9.7% of its revenue in the Asia-Pacific region last year, according to data compiled by Bloomberg, though that’s not broken down by individual countries.Sikorsky Aircraft Corp., which is owned by Lockheed, has a joint venture called Shanghai Sikorsky Aircraft Co. that does business with aviation companies and government-backed enterprises.“It’s a futile exercise that will have no direct effect on Lockheed Martin given that they aren’t allowed to sell anything to China,” said Nick Cunningham, an analyst at Agency Partners in London. “China may have a go at disrupting supplies, but that will only further accelerate the U.S. attempts at autarky.”Last week, the U.S. sanctioned a top member of China’s ruling Communist Party and three other officials over alleged abuses in the western province of Xinjiang. Then, on Monday, the Foreign Ministry announced unspecified sanctions against U.S. officials, including Senators Marco Rubio of Florida and Ted Cruz of Texas, after the Trump administration levied penalties on Chen Quanguo, who sits on the Communist Party’s 25-member Politburo.China previously threatened to sanction U.S. companies, including General Dynamics Corp. and Honeywell International Inc., on numerous occasions over arms sales to Taiwan. It also threatened to blacklist FedEx Corp., while Ford Motor Co.’s main joint venture partner in China was fined 162.8 million yuan ($23.6 million) last year, days after the U.S. put a ban on doing business with Huawei Technologies Co.Huawei is one of several Chinese technology companies in the sights of the Trump administration, which also is seeking to bar the telecommunications giant from advanced 5G wireless trials in countries such as the U.K and India.“This is completely just a countermeasure in response to the U.S. taking a more destructive approach to Taiwan and Hong Kong issues, and escalating long-arm jurisdiction,” said Tian Feilong, associate professor with the Law School of Beihang University.China and its state media have alluded to further action against U.S. companies, but the sanctions against Lockheed are a concrete move, signaling Beijing is willing to intensify its pushback as the U.S. criticizes it on political fronts like Hong Kong and the South China Sea.“It further confirms how we expect the Chinese government to behave in terms of international relationships,” said Steve Tsang, director of the SOAS China Institute in London. “There will be a lot of ‘you are either with us or against us,’ so companies will be forced to choose.”While China has often invoked the threat of putting U.S. companies on a blacklist — or list of “unreliable entities” — in response to various actions by the Trump administration over the past year, it has yet to name any, at least publicly.The U.S. last week also approved a military sale to Japan of 105 of Lockheed’s F-35 Joint Strike Fighter aircraft and related equipment for an estimated price of $23.1 billion.(Updates with more Foreign Ministry comment starting in second paragraph)For more articles like this, please visit us at bloomberg.comSubscribe now to stay ahead with the most trusted business news source.©2020 Bloomberg L.P.

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The latest 13F reporting period has come and gone, and Insider Monkey is again at the forefront when it comes to making use of this gold mine of data. We at Insider Monkey have plowed through 821 13F filings that hedge funds and well-known value investors are required to file by the SEC. The 13F […]

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